Manchester United defender Leny Yoro has made his first league outing since his arrival from Lille in the summer after he was listed on the bench by head coach Rubén Amorim.
United faces Arsenal at the Emirates in a Wednesday night Premier League classic.
United boss, Amorim makes key changes to his side that won 4-0 at Everton as Striker Rasmus Hojland returns to starting Lineup ahead of Joshua Zirkzee who scored a brace against the Toffees.
Malacia returns to the starting Lineup only for the second time since returning from his long term injury as Amad drops to the bench.
Harry Maguire who came on late against Everton starts ahead of Lizandro Martinez as Ugarte gets the nod ahead of Casemiro.
Arsenal XI: Raya, Timber, Saliba, Kiwior, Zinchenko, Rice, Partey, Saka, Ødegaard, Martinelli, Havertz
Man Utd XI: Onana, Dalot, Mazraoui, De Ligt, Maguire, Malacia, Ugarte, Bruno Fernandes, Mason Mount, Garnacho, Hojlund
